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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
26.67
Human Site:
Y257
Identified Species:
45.13
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
Y257
L
K
S
S
L
P
D
Y
R
A
A
T
Y
M
I
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
Y257
L
K
S
S
L
P
D
Y
R
A
A
T
Y
M
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
Y257
L
K
S
S
L
P
D
Y
R
A
A
T
Y
M
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
Y257
L
K
S
S
L
P
D
Y
R
A
A
T
Y
M
I
Rat
Rattus norvegicus
NP_001101888
2143
241191
Y257
L
K
S
S
L
A
D
Y
R
A
A
T
Y
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
Y257
L
K
S
S
V
Q
D
Y
R
A
A
T
Y
M
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
Y259
L
K
S
N
L
S
D
Y
T
A
A
T
Y
M
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
A258
D
N
I
D
F
M
A
A
A
Y
V
I
V
A
Q
Honey Bee
Apis mellifera
XP_393800
2028
231830
F254
L
E
S
S
I
A
D
F
A
A
S
T
Y
M
I
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
L258
L
D
Q
Q
A
G
A
L
M
V
V
G
M
L
A
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
A67
S
Q
I
E
P
K
F
A
I
F
S
R
T
L
F
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
S86
E
A
D
R
T
Q
M
S
A
A
E
N
A
A
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
N.A.
86.6
N.A.
80
N.A.
0
60
0
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
N.A.
93.3
N.A.
86.6
N.A.
0
86.6
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
15
15
15
22
65
50
0
8
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
0
58
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
8
8
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
8
0
0
0
8
0
0
8
0
0
58
% I
% Lys:
0
50
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
65
0
0
0
43
0
0
8
0
0
0
0
0
15
8
% L
% Met:
0
0
0
0
0
8
8
0
8
0
0
0
8
58
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
29
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
8
0
15
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
43
0
0
8
0
0
0
% R
% Ser:
8
0
58
50
0
8
0
8
0
0
15
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
0
58
8
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
8
15
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
8
0
0
58
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _